Synergistics
: Fungal Infections


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Medication Store > Fungal Infections
Lamisil
Lamisil

Terbinafine (TER-bin-a-feen) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
Terbinafine is applied to the skin to treat:

  • ringworm of the body (tinea corporis);
  • ringworm of the foot (interdigital and plantar tinea pedis; athlete's foot);
  • ringworm of the groin (tinea cruris; jock itch);
  • tinea versicolor (sometimes called “sun fungus”); and
  • yeast infection of the skin (cutaneous candidiasis).
Lotrimin Cream
Lotrimin Cream

Lotrimin
This page contains drug information on Lotrimin.
The information provided includes the following:
what is Lotrimin
the possible side effects of Lotrimin
what happens if you miss a dose of Lotrimin
what happens if you overdose with Lotrimin
the most important information about Lotrimin
how to use Lotrimin
other drugs that may affect Lotrimin
what to avoid while using Lotrimin


Generic Name: clotrimazole topical (kloe TRIM a zole)
Brand Names: Desenex AF Prescription Strength, Fungoid Solution, Lotrimin, Lotrimin Jock Itch Powder, Mycelex, Mycelex OTC


What is the most important information I should know about clotrimazole topical?

  • Use this medication for the full amount of time prescribed by your doctor or as recommended in the package even if you begin to feel better. Your symptoms may improve before the infection is completely healed.
  • Do not use bandages or dressings that do not allow air to circulate to the affected area (occlusive dressings) unless otherwise directed by your doctor. Wear loose-fitting clothing (preferably cotton).
  • Avoid getting this medication in your eyes, nose, or mouth.

What is clotrimazole topical?

  • Clotrimazole topical is an antifungal medication. Clotrimazole topical prevents fungus from growing on your skin.
  • Clotrimazole topical is used to treat skin infections such as athlete's foot, jock itch, ringworm, and yeast infections.
  • Clotrimazole topical may also be used for purposes other than those listed in this medication guide.

Who should not use clotrimazole topical?

  • Do not use clotrimazole topical if you have had an allergic reaction to it in the past.
  • Clotrimazole topical is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not use clotrimazole topical without first talking to your doctor if you are pregnant.
  • It is not known whether clotrimazole passes into breast milk. Do not use clotrimazole topical without first talking to your doctor if you are breast-feeding a baby.

How should I use clotrimazole topical?

  • Use clotrimazole topical exactly as directed by your doctor or follow the directions that accompany the package. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Wash your hands before and after using this medication, unless you are using it to treat a hand infection.
  • Clean and dry the affected area. Apply a small amount of the cream (usually twice daily) for 2 to 4 weeks.
  • Do not take this medication by mouth.
  • If the infection does not clear up in 4 weeks, or if it appears to get worse, see your doctor.
  • Use this medication for the full amount of time prescribed by your doctor or as recommended in the package even if you begin to feel better. Your symptoms may improve before the infection is completely healed.
  • Do not use bandages or dressings that do not allow air circulation over the affected area (occlusive dressings) unless otherwise directed by your doctor. A light cotton-gauze dressing may be used to protect clothing.
  • Avoid getting this medication in your eyes, nose, or mouth.
  • Store clotrimazole topical at room temperature away from moisture and heat.

What happens if I miss a dose?

  • Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the dose you missed and apply only the regular amount of clotrimazole topical. Do not use a double dose unless otherwise directed by your doctor.

What happens if I overdose?

  • An overdose of clotrimazole topical is unlikely to occur. If you do suspect that a much larger than normal dose has been used, or that clotrimazole topical has been ingested, contact an emergency room or a poison control left.

What should I avoid while using clotrimazole topical?

  • Avoid wearing tight-fitting, synthetic clothing that doesn't allow air circulation. Wear clothing made of loose cotton and other natural fibers until the infection is healed.

What are the possible side effects of clotrimazole topical?

  • Serious side effects of clotrimazole topical use are not expected. Stop using clotrimazole topical and see your doctor if you experience unusual or severe blistering, itching, redness, peeling, dryness, swelling, or irritation of the skin.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect clotrimazole topical?

  • Avoid using other topicals at the same time unless your doctor approves. Other skin medications may affect the absorption or effectiveness of clotrimazole topical.
  • Drugs other than those listed here may also interact with clotrimazole topical. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines.
Sporanox
Sporanox

Sporanox
This page contains drug information on Sporanox.
The information provided includes the following:
what is Sporanox
the possible side effects of Sporanox
what happens if you miss a dose of Sporanox
what happens if you overdose with Sporanox
the most important information about Sporanox
how to use Sporanox
other drugs that may affect Sporanox
what to avoid while using Sporanox


Generic Name: itraconazole (ih tra CAW nah zole)
Brand Names: Sporanox


What is the most important information I should know about itraconazole?

  • Do not take itraconazole if you are taking astemizole (Hismanal), cisapride (Propulsid), pimozide (Orap), triazolam (Halcion), midazolam (Versed), lovastatin (Mevacor), simvastatin (Zocor), or quinidine (Cardioquin, Quinora, Quinidex, Quinaglute, Quin-Release, Quin-G). Combined with these drugs, itraconazole could cause serious, even fatal, problems.
  • In rare cases, itraconazole has caused severe liver damage, sometimes resulting in death. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, yellow skin or eyes, itching, dark urine, or clay colored stools. These symptoms may be early signs of liver damage.
  • In rare cases, itraconazole has been associated with the onset of congestive heart failure (CHF). Do not take itraconazole without first talking to your doctor if you have CHF or a history of CHF; other heart or heart valve disease; a lung disease such as chronic obstructive pulmonary disease; or significant swelling or water retention (edema). Contact your doctor if you develop symptoms that may indicate CHF including shortness of breath, chest pain, or swelling during treatment with itraconazole.
  • Take all of the itraconazole that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

What is itraconazole?

  • Itraconazole is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.
  • Itraconazole is used to treat fungal infections in the lungs, in the central nervous system, in other parts of the body, as well as serious fungal infections of the skin and nails. The itraconazole oral solution is used to treat yeast infections of the mouth, throat, and esophagus.
  • Itraconazole may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking itraconazole?

Do not take itraconazole if you are taking any of the following drugs:

  • astemizole (Hismanal);
  • cisapride (Propulsid);
  • pimozide (Orap);
  • quinidine (Cardioquin, Quinora, Quinidex, Quinaglute, Quin-Release, Quin-G);
  • midazolam (Versed) or triazolam (Halcion); or
  • lovastatin (Mevacor) or simvastatin (Zocor).

Dangerous or life-threatening events may occur if itraconazole is taken with any of the medicines listed above.

In rare cases, itraconazole has been associated with the onset of congestive heart failure (CHF). Do not take itraconazole without first talking to your doctor if you have CHF or a history of CHF; other heart or heart valve disease; a lung disease such as chronic obstructive pulmonary disease; or significant swelling or water retention (edema). Contact your doctor if you develop symptoms that may indicate CHF including shortness of breath, chest pain, or swelling during treatment with itraconazole.

Before taking itraconazole, tell your doctor if you have

  • liver disease; or
  • achlorhydria (decreased stomach acid production) or if you take antacids, stomach acid reducers, or stomach ulcer medicines.

You may not be able to take itraconazole, or you may require a dosage adjustment, special monitoring, or special directions for use during your treatment.

Itraconazole is in the FDA pregnancy category C. This means that it is not known whether itraconazole will be harmful to an unborn baby. Effective contraception is recommended for any woman who could potentially become pregnant during treatment with itraconazole and for 2 months following the end of treatment. Do not take this medication without first talking to your doctor if you are pregnant.

Itraconazole passes into breast milk and may affect a nursing infant. Do not take itraconazole without first talking to your doctor if you are breast-feeding a baby.

How should I take itraconazole?

  • Take itraconazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each capsule with a full glass of water.
  • Take itraconazole capsules after a full meal to increase absorption in your stomach.
  • To treat yeast infections of the mouth, throat, or esophagus, the oral solution should be swished vigorously in the mouth for several seconds, then swallowed. Take the oral solution without food if possible.
  • Itraconazole capsules and oral solution are different preparations and cannot be used interchangeably.
  • Take all of the itraconazole that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.
  • Grapefruit and grapefruit juice may interact with itraconazole. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
  • Store itraconazole at room temperature away from moisture and heat.

What happens if I miss a dose?

  • Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

  • Seek emergency medical attention if an overdose is suspected.
  • Symptoms of an itraconazole overdose are not well known but might include dizziness, ringing in the ears, headache, nausea, vomiting, diarrhea, and abdominal pain.

What should I avoid while taking itraconazole?

  • Use alcohol with moderation while taking itraconazole. Alcohol and itraconazole can both affect the liver.
  • Use caution when driving or performing other hazardous activities. Itraconazole may cause dizziness. If you experience dizziness, avoid these activities.
  • Grapefruit and grapefruit juice may interact with itraconazole. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What are the possible side effects of itraconazole?

If you experience any of the following serious side effects, stop taking itraconazole and seek emergency medical attention or notify your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • liver damage (pale stools, yellowish skin or eyes, abdominal pain, unusual fatigue, or dark urine);
  • symptoms of congestive heart failure including shortness of breath, chest pain, or swelling; or
  • nerve pain, numbness or tingling.
  • Other, less serious side effects may be more likely to occur. If you experience any of the following side effects, continue taking itraconazole and talk to your doctor:

  • nausea, vomiting, or diarrhea;
  • headache;
  • dizziness;
  • fatigue; or
  • itching or a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect itraconazole?

Do not take itraconazole if you are taking any of the following drugs:

  • astemizole (Hismanal);
  • cisapride (Propulsid);
  • pimozide (Orap);
  • quinidine (Cardioquin, Quinora, Quinidex, Quinaglute, Quin-Release, Quin-G);
  • midazolam (Versed) or triazolam (Halcion); or
  • lovastatin (Mevacor) or simvastatin (Zocor).

Dangerous or life-threatening events may occur if itraconazole is taken with any of the medicines listed above.

Before taking itraconazole, tell your doctor if you are taking any other medicines, especially any of the following:

  • digoxin (Lanoxin, Lanoxicaps);
  • carbamazepine (Tegretol, others) or phenytoin (Dilantin, others);
  • rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane);
  • busulfan (Myleran), docetaxel (Taxotere), vinblastine sulfate (Velban), vincristine sulfate (Oncovin), or vinorelbine (Navelbine);
  • trimetrexate (Neutrexin);
  • alprazolam (Xanax) or diazepam (Valium);
  • verapamil (Isoptin, Verelan, Calan, Covera-HS), amlodipine (Norvasc), felodipine (Plendil), isradipine (DynaCirc),nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), or nisoldipine (Sular);
  • atorvastatin (Lipitor) or cerivastatin (Baycol);
  • tacrolimus (Prograf);
  • sirolimus (Rapamune);
  • cyclosporine (Sandimmune, Neoral);
  • glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others;
  • indinavir (Crixivan), ritonavir (Norvir), or saquinavir (Fortovase, Invirase);
  • buspirone (Buspar);
  • antacids;
  • cimetidine (Tagamet, Tagamet HB), nizatidine (Axid, Axid AR), famotidine (Pepcid, Pepcid AC), or ranitidine (Zantac, Zantac 75);
  • omeprazole (Prilosec), lansoprazole (Prevacid), or rabeprazole (Aciphex);
  • isoniazid (Nydrazid);
  • nevirapine (Viramune);
  • methylprednisolone (Medrol, others);
  • clarithromycin (Biaxin); or
  • warfarin (Coumadin).

You may not be able to take itraconazole, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with itraconazole or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.